Parkinson's in the Media

Parkinson's Disease Stopped in Animal Model:  Molecular 'Tweezers' Break Up Toxic Aggregations of Proteins
Science Daily
UCLA professor of neurology Jeff Bronstein and UCLA associate professor of neurology Gal Bitan, along with their colleagues, report the development of a novel compound known as a "molecular tweezer," which in a living animal model blocked a-synuclein aggregates from forming, stopped the aggregates' toxicity and, further, reversed aggregates in the brain that had already formed. And the tweezers accomplished this without interfering with normal brain function.  The research appears in the current online edition of the journal NeurotherapeuticsMore...

Vets Feel Abandoned After Secret Drug Experiments
But Josephs, 63, believes the chemical agents he received during his two-month stint at Edgewood did harm him, triggering health problems that continue to plague him four decades later.  Even when he talks about Edgewood, he said, "I get a tightness in my chest." Days before his Edgewood duty ended, in February 1968, Josephs was hospitalized for days with Parkinson's-like tremors, symptoms he said have followed him on and off throughout his adult life.  From Edgewood, Josephs said he went to an Army installation in Georgia, where he experienced tremors so severe, he had to be admitted to the base hospital and given muscle relaxers.  The Army then sent Josephs to Air Force bases in Thailand, in support of the war effort in Vietnam.  He was told never to talk about his experiences at Edgewood and to forget about everything he ever did, said or heard at the Maryland base.  More...

Parkinson's Pump Offers Steady Relief
WKYC-TV (NBC affiliate; Cleveland, OH)
Bob Van Housen's advanced Parkinson's disease claimed his mobility.  He couldn't walk in the morning until his oral medication, the standard Levodopa, would kick in.  Usually that took around ninety minutes.  His life was unpredictable because he never knew when the symptoms would appear.  He also needed to take four pills every three hours.  Levodopa has been on the market since 1969.  It's a cheap and reliable first line of treatment for many.  But as the disease progresses, Levodopa often wears off sooner.  Bob's situation is not uncommon for many Parkinson's patients so when he had the opportunity to join a clinical trial at Cleveland Clinic testing a new way to deliver the drug, he took the chance.  More...

REM Sleep Disorder Doubles Risk of Mild Cognitive Impairment, Parkinson's

Mayo Clinic Announcement (Press Release)
People with symptoms suggesting rapid eye movement sleep behavior disorder have twice the risk of developing mild cognitive impairment or Parkinson's disease within four years of diagnosis with the sleep problem, compared with people without the disorder, a Mayo Clinic study has found. The researchers published their findings recently in the Annals of Neurology.  More...

Statins Tied to Slightly Lower Risk of Parkinson's
Chicago Tribune (Reuters)
People taking statins have a slightly lower risk of developing Parkinson's disease than those not on the cholesterol-lowering drugs, suggests a new study.  The findings don't mean that taking statins will ward off the degenerative movement disorder, and the researchers behind the new study say evidence that there's a link between the drugs and Parkinson's "remains unconvincing."  "Nobody should start or stop statins based on this result," Dr. Alberto Ascherio from the Harvard School of Public Health, one of the researchers, told Reuters Health.  More...

New Blood Test That Could Diagnose Parkinson's Is Being Studied
Michael J. Fox Foundation Blog
WebMD is reporting on a potential blood test (a.k.a. biomarker) for Parkinson's disease that's resulted from a project funded by The Michael J. Fox Foundation.  According to our own VP of Research Programs Mark Frasier, it's still early days and the finding requires replication through PPMI — but it looks promising.  The work was carried out by Robert Nagele of Durin Technologies and the University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine.  More...


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